{"id":116204,"date":"2024-06-19T12:16:33","date_gmt":"2024-06-19T16:16:33","guid":{"rendered":"https:\/\/interamerica.org\/?p=116204"},"modified":"2024-06-24T12:58:14","modified_gmt":"2024-06-24T16:58:14","slug":"le-centre-medical-de-luniversite-de-loma-linda-presente-une-therapie-genique-transformatrice-contre-lhemophilie","status":"publish","type":"post","link":"https:\/\/interamerica.org\/fr\/2024\/06\/le-centre-medical-de-luniversite-de-loma-linda-presente-une-therapie-genique-transformatrice-contre-lhemophilie\/","title":{"rendered":"Le Centre m\u00e9dical de l\u2019Universit\u00e9 de Loma Linda pr\u00e9sente une th\u00e9rapie g\u00e9nique transformatrice contre l\u2019h\u00e9mophilie"},"content":{"rendered":"

L\u2019\u00e9tablissement adventiste offre une th\u00e9rapie g\u00e9n\u00e9tique de pointe qui peut transformer la vie des enfants et des adultes qui souffrent de telles conditions handicapantes.<\/span><\/i><\/p>\n

Le 19 juin 2024 | Loma Linda, Californie, \u00c9tats-Unis | Linda Ha<\/span><\/p>\n

Le Programme d\u2019h\u00e9mophilie du Centre m\u00e9dical de l\u2019Universit\u00e9 de Loma Linda (LLUH pour <\/span>Loma Linda University Health<\/span><\/i>) offre maintenant le traitement HEMGENIX, la premi\u00e8re th\u00e9rapie g\u00e9nique approuv\u00e9e par la FDA contre l\u2019h\u00e9mophilie B, en plus du \u00ab\u00a0dirloctocogene samoparvovec\u00a0\u00bb, une th\u00e9rapie g\u00e9nique de pointe de deuxi\u00e8me g\u00e9n\u00e9ration contre l\u2019h\u00e9mophilie A. Cette innovation a le potentiel de transformer la vie d\u2019innombrables patients, enfants et adultes, souffrant de cette condition handicapante.<\/span><\/p>\n

L\u2019h\u00e9mophilie est un trouble g\u00e9n\u00e9tique qui affecte la capacit\u00e9 du sang \u00e0 coaguler et qui diminue la qualit\u00e9 de vie de ceux qui en souffrent. Elle peut transformer les blessures mineures en \u00e9normes risques pour la sant\u00e9, car elle peut causer des saignements incontr\u00f4lables. D\u2019apr\u00e8s la Biblioth\u00e8que nationale de m\u00e9decine, on l\u2019appelle souvent la \u00ab\u00a0maladie royale\u00a0\u00bb, \u00e9tant donn\u00e9 sa pr\u00e9valence parmi les descendants de la reine Victoria (Royaume-Uni), elle qui \u00e9tait porteuse de l\u2019h\u00e9mophilie, ce trouble g\u00e9n\u00e9tique qui affecte la capacit\u00e9 du sang \u00e0 coaguler, occasionnant des saignements excessifs lors des blessures mineures. Le trouble est g\u00e9n\u00e9ralement transmis par le chromosome X, la raison pour laquelle il affecte principalement les hommes, alors que les femmes en sont g\u00e9n\u00e9ralement les porteuses. L\u2019h\u00e9mophilie peut transformer les blessures mineures en risques importants pour la sant\u00e9 \u00e9tant donn\u00e9 les saignements incontr\u00f4lables qu\u2019elle occasionne.<\/span><\/p>\n

\"\"

Le docteur Jain et son patient h\u00e9mophile, Edgar Larios. [Une photo de l\u2019Universit\u00e9 de Loma Linda]<\/span><\/p><\/div>Auparavant, pour ma\u00eetriser leur h\u00e9mophilie, les patients devaient s\u2019injecter eux-m\u00eames des facteurs de coagulation, et ce, plusieurs fois par semaine afin d\u2019\u00e9viter les \u00e9pisodes dangereux de saignements, un traitement tout aussi douloureux que restrictif.<\/span><\/p>\n

Le traitement HEMGENIX permet dor\u00e9navant aux patients de produire leurs propres facteurs de coagulation, qu\u2019ils n\u2019ont pas naturellement. Ce traitement administr\u00e9 qu\u2019une seule fois consiste en une infusion de trois heures qui transmet au foie un g\u00e8ne modifi\u00e9, permettant la production naturelle de facteurs de coagulation.<\/span><\/p>\n

\u00ab\u00a0HEMGENIX s\u2019est av\u00e9r\u00e9 \u00eatre un traitement transformateur pour les patients, a dit le docteur <\/span>Akshat Jain<\/span><\/a>, directeur des Troubles de saignements h\u00e9r\u00e9ditaires de l\u2019h\u00f4pital pour enfants de l\u2019Universit\u00e9 de Loma Linda. Il augmente les taux de facteurs de coagulation, les faisant passer de moins de 1\u00a0% \u00e0 environ 30 \u00e0 40\u00a0%, une am\u00e9lioration incroyable. Bien que l\u2019intervalle normal commence \u00e0 55\u00a0%, cette augmentation r\u00e9duit consid\u00e9rablement la fr\u00e9quence et la gravit\u00e9 des \u00e9pisodes de saignement, permettant aux patients de vivre quasi normalement.\u00a0\u00bb<\/span><\/p>\n

Les patients peuvent marcher, faire du sport et travailler sans la peur constante de se mettre \u00e0 saigner dangereusement.<\/span><\/p>\n

Edgar Larios, 18 ans, est un patient h\u00e9mophile pour qui l\u2019on consid\u00e8re le traitement par th\u00e9rapie g\u00e9nique. \u00ab\u00a0Ma vie serait compl\u00e8tement transform\u00e9e, car je n\u2019aurais plus \u00e0 m\u2019injecter des centaines de fois et je pourrais \u00eatre plus actif sans craindre constamment l\u2019h\u00e9morragie\u00a0\u00bb, a-t-il dit.<\/span><\/p>\n

Le LLUH a structur\u00e9 son programme de mani\u00e8re \u00e0 s\u2019assurer que les contraintes financi\u00e8res ne bloquent pas l\u2019acc\u00e8s \u00e0 ce traitement transformateur, car bien des patients d\u00e9pendent de Medicare ou de Medicaid.<\/span><\/p>\n

\u00ab\u00a0L\u2019approche holistique de notre centre comprend les infrastructures compl\u00e8tes et les protocoles de s\u00e9curit\u00e9 pour administrer le traitement g\u00e9nique, a expliqu\u00e9 le Dr Jain. Nous sommes l\u2019un des quelques h\u00f4pitaux aux \u00c9tats-Unis \u00e0 offrir ce traitement de pointe et le seul de l\u2019Inland Empire \u00e0 \u00eatre organis\u00e9 pour le faire.\u00a0\u00bb<\/span><\/p>\n

Pour plus de renseignements sur le programme contre l\u2019h\u00e9mophilie du Centre m\u00e9dical de l\u2019Universit\u00e9 de Loma Linda, voici le <\/span>lien<\/span><\/a>.<\/span><\/p>\n

Traduction\u00a0: Marie-Mich\u00e8le Robitaille<\/span><\/p>\n","protected":false},"excerpt":{"rendered":"

L\u2019\u00e9tablissement adventiste offre une th\u00e9rapie g\u00e9n\u00e9tique de pointe qui peut transformer la vie des enfants et des adultes qui souffrent de telles conditions handicapantes. Le 19 juin 2024 | Loma…<\/p>\n","protected":false},"author":3,"featured_media":116091,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[18,19],"tags":[],"class_list":["post-116204","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-nouvelles-de-leglise-mondiale","category-rss-francais"],"acf":[],"yoast_head":"\nLe Centre m\u00e9dical de l\u2019Universit\u00e9 de Loma Linda pr\u00e9sente une th\u00e9rapie g\u00e9nique transformatrice contre l\u2019h\u00e9mophilie - \u00c9glise Adventiste Du Septieme Jour - Inter Am\u00e9rique Division<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/interamerica.org\/fr\/2024\/06\/le-centre-medical-de-luniversite-de-loma-linda-presente-une-therapie-genique-transformatrice-contre-lhemophilie\/\" \/>\n<meta property=\"og:locale\" content=\"fr_FR\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Le Centre m\u00e9dical de l\u2019Universit\u00e9 de Loma Linda pr\u00e9sente une th\u00e9rapie g\u00e9nique transformatrice contre l\u2019h\u00e9mophilie - \u00c9glise Adventiste Du Septieme Jour - Inter Am\u00e9rique Division\" \/>\n<meta property=\"og:description\" content=\"L\u2019\u00e9tablissement adventiste offre une th\u00e9rapie g\u00e9n\u00e9tique de pointe qui peut transformer la vie des enfants et des adultes qui souffrent de telles conditions handicapantes. 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